In this work, a vulcanized blend of natural rubber (NR) and styrene butadiene rubber (SBR) (i.e. at weight ratio of 50[thin space (1/6-em)]:[thin space (1/6-em)]50) as a model for tire rubber was devulcanized using probe sonication. The effect of processing parameters such as sonication media, power, temperature and time on sol/gel contents and devulcanization percent of rubbery samples was investigated. Moreover, the influence of pre-immersion of vulcanized NR/SBR samples in different liquids (i.e. water, oil and toluene) was assessed for different sonication times (i.e. 10 to 60 min) and powers (i.e. 30 to 60 W). It was found that pre-immersion of rubber particles in oil significantly increased the devulcanization percent. The optimum conditions for devulcanization of the NR/SBR blend via probe sonication were found to be 60 Watts, 20 min, oil and 24 h for sonication power, sonication time, pre-immersion/sonication media and pre-immersion time, respectively. The highest obtained devulcanization percent in this step was about 40%. The effects of two devulcanizing chemical agents (i.e. diphenyl disulfide and VitaX) on devulcanization performances of the samples were also studied. Results showed that higher devulcanization percent (i.e. about 52%) was obtained by using VitaX. It was also observed that VitaX significantly improved re-vulcanization speed (i.e. cure rate index) and decreased scorch time. It was also found that lower content of VitaX (i.e. 0.6 phr) caused better curing properties but lower mechanical properties compared to the higher content (i.e. 1.2 phr).